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Which of the statements below best describes high affinity interactions between

ID: 3515394 • Letter: W

Question

Which of the statements below best describes high affinity interactions between a neutrophil and endothelial cell? ICAM-1 on leukocytes binds to LFA-1 on endothelial cells, acting as a "brake" to slow leukocytes down against blood flow. ICAM-1 on endothelial cells binds to LFA-1 on leukocytes, acting as a "brake" to slow leukocytes down against blood flow. O ICAM-1 on leukocytes binds to LFA-1 on endothelial cells to mediate stable arrest. O ICAM-1 on endothelial cells binds to LFA-1 on leukocytes to mediate stable arrest

Explanation / Answer

ICAM-1 on endothelial cells binds to LFA-1 on leukocytes, actiing as "brake" to slow leukocytes down against blood flow.

ICAM-1 on endothelial cells binds to LFA-1 on leukoctyes to mediate stable arrest.

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