Procedure 1 Model Inventory for Parts of the Synapze Identify the pars of the sy

Question

Procedure 1 Model Inventory for Parts of the Synapze Identify the pars of the symapse on models and diagrams using your you examine the anatomical models and textbook and this unit for reference. As able to identify on the model inventory in Table 12.1 (note that this is the model inventor 321) the name 12-1.p. 1. Parts of the synapse from Exercise I rts of the nventory in Table 13gras, recard the name of the sodel and the structures you were a. Presynaptic neuron b. Axon terminal c. Synaptic vesicle d. Synaptic cleft e. Postsynaptic neuron . Neurotransmitter receptors Procedure 2 Time to Trace! 12 transmission Lets now trace the entire series of events through a three-necuron loop, including the steps of synaptc tr berween neurons 1 and 2, the propagation potential down transmission that occur hetween of the action potential down the axon of neuron 2, and the steps of synaptsc neuron 2 and 3. Hints are included to ensure that you stay on the right rrack as you When you have completed the activity answer Check Your Understanding questions 5 through 7 (p 332). Start: neuronal action potential reaches the axon terminal of neuron 1 -> from the axon terminal by are released diffuse across the on the enough and bind to postsynapnc membrane of neuron 2, generating an excitatory local potential ? times, the excitatory local potentials toward the axon->when the trigger zone is depolarized to f the neuron is stimulated and spread through the neuron's plasma membrane .an is generated, which down the axon until it reaches the axon terminals ? depolarization of the axon terminal triggers the opening of ion channels, and these ions enter the axon terminal are released from the axon terminal by diffuse across the on the postsynaptic membrane of neuron 3, generating an excitatory or inhibitory local potential. End and bind to

Explanation / Answer

Neuronal action potential reaches the axon terminal of neuron 1. Acetyl choline (ACh) molecules are released from the axon terminal by exocytosis. ACh diffuse across the synaptic cleft and bind to ligand-gated Na+ receptors on the postsynaptic membrane of neuron 2, generating an excitatory local potential. If the neuron is stimulated enough times, the excitatory local potential summate and spread through the neuron's plasma membrane towards the axon. When the trigger zone is depolarized to threshold, an action potential is generated which spreads down the axon untill it reaches the axon terminals. Depolarixation of the axon terminal triggers the opening of voltage gated Ca2+ ion channels and these ions enters the axon terminal. Acetyl choline (ACh) molecules are released from the axon terminal by exocytosis. ACh diffuse across the synaptic cleft and bind to ligand-gated Na+ receptors on the postsynaptic membrane of neuron 3, generating an excitatory local potential.

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