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This 30-year-old female was diagnosed with MS two years prior to seeking help fr

ID: 3513573 • Letter: T

Question

This 30-year-old female was diagnosed with MS two years prior to seeking help from upper cervical care. Her diagnosis had been given after multiple episodes of optic neuritis, fatigue, tingling in her extremities, foot drop, and loss of bladder control. At the time of her initial evaluation, her main symptoms included pain, stiffness, and weakness in her right hip, pelvis, and leg; bladder hesitancy; fatigue; blurred vision; tightness in her neck and shoulders; trouble sleeping; and inability to walk without a cane.

What is the pathogenesis of the disease?

Does multiple sclerosis affect CNS, PNS ot both? Why?


This 30-year-old female was diagnosed with MS two years prior to seeking help from upper cervical care. Her diagnosis had been given after multiple episodes of optic neuritis, fatigue, tingling in her extremities, foot drop, and loss of bladder control. At the time of her initial evaluation, her main symptoms included pain, stiffness, and weakness in her right hip, pelvis, and leg; bladder hesitancy; fatigue; blurred vision; tightness in her neck and shoulders; trouble sleeping; and inability to walk without a cane.

What is the pathogenesis of the disease?

Does multiple sclerosis affect CNS, PNS ot both? Why?



11

Explanation / Answer

Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.

There is no known cure for multiple sclerosis

Myelin is present in the central nervous system (CNS) and peripheral nervous system (PNS); however only the central nervous system is affected by MS. CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells.

In MS, an abnormal immune system response produces inflammation in the central nervous system. This process:

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