Which of the following statements about blood flowing in the coronary arteries i
ID: 3511703 • Letter: W
Question
Which of the following statements about blood flowing in the coronary arteries is/are true? Choose all that apply. A) coronary arteries fill more when HR increases B) pressure generated by the myocardium during ventricular contraction increases flow C) flow is high during diastole and low during systole D) major determinant of flow is the metabolic activity of cardiomyocytes E) nitric oxide increases flow while ET-1 decreases flow Which of the following statements about blood flowing in the coronary arteries is/are true? Choose all that apply. A) coronary arteries fill more when HR increases B) pressure generated by the myocardium during ventricular contraction increases flow C) flow is high during diastole and low during systole D) major determinant of flow is the metabolic activity of cardiomyocytes E) nitric oxide increases flow while ET-1 decreases flow A) coronary arteries fill more when HR increases B) pressure generated by the myocardium during ventricular contraction increases flow C) flow is high during diastole and low during systole D) major determinant of flow is the metabolic activity of cardiomyocytes E) nitric oxide increases flow while ET-1 decreases flowExplanation / Answer
Ans.
A-TRUE
When heart rate increases, the myocardial oxygen consumption per minute also increases and as a result the coronary blood flow also increases
B-FALSE
During ventricular contraction, the coronary arteries are squeezed in betwwen and as a result the blood flow decreases.
C-TRUE
During systole when the heart contracts, the coronary arteries are compressed and twisted which highly reduces the flow and during diastole, when the heart muscle relaxes, the blood flow is resumed thus flow is high during diastole and low during systole.
D-FALSE
The major determinant of coronary blood flow is oxygen demand.
E-TRUE
Nitric oxide being a vasodilator, decreases the resistance and increases the blood flow, Endothelein 1 (ET1) being a vasoconstrictor, increases the constriction and decreases the blood flow
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