1. Consider this endocrine sequence. When the M cell is active, the M cell relea
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Question
1. Consider this endocrine sequence. When the M cell is active, the M cell releases hormone M. M activates the M receptor. When M receptor is activated on I cells, I cell releases I. I activates the I receptor. When the I receptor is activated, the Z cell decreases the release of Z. When Z cells release Z, ZOU is reabsorbed from tubule to the blood. So when the I receptor is activated, ZOU is NOT reabsorbed from tubule to blood. Z activates the Z receptor. When the Z receptor is activated on M cells, M cells release hormone M.1a. Drug 1 makes the I receptor always active. What happens to ZOU in the blood, does it increase or decrease? Explain. How do the concentrations of M, I, and Z compare to those without the drug present? Explain.
1b. Drug 2 makes the M cell always active/releasing M. What happens to ZOU in the blood, does it increase or decrease? Explain. How do the concentrations of M, I, and Z compare to those without the drug present? Explain.
1. Consider this endocrine sequence. When the M cell is active, the M cell releases hormone M. M activates the M receptor. When M receptor is activated on I cells, I cell releases I. I activates the I receptor. When the I receptor is activated, the Z cell decreases the release of Z. When Z cells release Z, ZOU is reabsorbed from tubule to the blood. So when the I receptor is activated, ZOU is NOT reabsorbed from tubule to blood. Z activates the Z receptor. When the Z receptor is activated on M cells, M cells release hormone M.
1a. Drug 1 makes the I receptor always active. What happens to ZOU in the blood, does it increase or decrease? Explain. How do the concentrations of M, I, and Z compare to those without the drug present? Explain.
1b. Drug 2 makes the M cell always active/releasing M. What happens to ZOU in the blood, does it increase or decrease? Explain. How do the concentrations of M, I, and Z compare to those without the drug present? Explain.
1. Consider this endocrine sequence. When the M cell is active, the M cell releases hormone M. M activates the M receptor. When M receptor is activated on I cells, I cell releases I. I activates the I receptor. When the I receptor is activated, the Z cell decreases the release of Z. When Z cells release Z, ZOU is reabsorbed from tubule to the blood. So when the I receptor is activated, ZOU is NOT reabsorbed from tubule to blood. Z activates the Z receptor. When the Z receptor is activated on M cells, M cells release hormone M.
1a. Drug 1 makes the I receptor always active. What happens to ZOU in the blood, does it increase or decrease? Explain. How do the concentrations of M, I, and Z compare to those without the drug present? Explain.
1b. Drug 2 makes the M cell always active/releasing M. What happens to ZOU in the blood, does it increase or decrease? Explain. How do the concentrations of M, I, and Z compare to those without the drug present? Explain.
Explanation / Answer
1a . Drug one is making the I receptor always active .
As we know as the I receptor is activated , the release of the Z by the Z cells is decreased . Z cells helsp in reabsorbtion of the ZOU from the tubule to the blood .
So , when Z release is decreased , it will lead to les reabsorbtion of ZOU in the blood . Therefore it decreases in the blood .
Also , Z also activates the Z receptors present kn M cells , increasing the release of M hormone .
Therefore , less M hormones will be released , decreasing there concentration in the blood .
As M is activating the I cells , less M will cause less I to release .its concentration will also decrease .
But I causes decrease of the release of Z from the Z cell .,Therefore the decrease in the concentration of I will increase the release of Z .
1b. Drug 2 activates the M cell to release hormone M .
All the things mentioned in the question will happen , therefore ZOU will decrease in the blood .
The concentration of M will , I increases, Z decreased by the drug 2.
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