48 Myasthenia gravis results from: A. a clostridium toxin; B. autoimmune reactio

Question

48 Myasthenia gravis results from:

A.      a clostridium toxin;

B.      autoimmune reaction against nicotinic receptors;

C.      malignant hyperthermia;

D.      Organophosphate esters;;:

49. Where is calcium not used?

A.       Troponin binding              C.       Ach release at alpha motor neuron

B.       Bone growth           D.       Saltatory conduction

50. The end-to-end arrangement of sarcomeres is a:

a. myofiber                      c. myoblast

b. myofilament                 d. myofibril

Explanation / Answer

48.Myasthenia gravis is a autoimmune neuromuscular disorder which affects the skeletal muscles used for movements. It is a very rare disorder in which antibodies are formed against the acetylcholine nicotinic receptors at the post synaptic junction of the skeletal muscles. These antibodies destroys the receptors and results in weakness of the skeletal muscles.

So the answer is B. Autoimmune reaction against the nicotinic receptors.

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