3. Examine the blood values in Table 1. The following tests from Table 1 were fo

Question

3. Examine the blood values in Table 1. The following tests from Table 1 were found to have abnormal values. Indicate whether the test value is higher or lower than normal, and if the result indicates an increased or decreased ability to form clots (5 pts) Higher or lower Would this indicate an increased than normal? Test or decreased ability to form clots? International normalized ratio Partial thromboplastin time (s) Fibrinogen (g/L) D-dimer, ng/mL FEU Coagulation Factor XIII (U/mL) 4. What step in the clotting pathway appears to be disrupted in this patient? Use figures 16-8 (hemostasis and tissue repair) and 16-10 (coagulation cascade) from your text, and explain what evidence led you to this conclusion. (3 pts) We diagnosed an atypical presentation of disseminated intravascular coagulation or primary fibrinolysis triggered by an unknown process. We started treatment with fresh frozen plasma, cryoprecipitate and fibrinogen concentrate. In view of her presenting signs and symptoms and travel history, we searched MEDLINE and Google Scholar, which revealed the possibility of caterpillar envenomation that could account for all her clinical symptoms and laboratory results

Explanation / Answer

TESTS

INR

HIGHER-INTERNATIONAL NORMALIZED RATIO INDICATES DECREASED ABILITY TO FORM BLOOD CLOT

LOWER-INTERNATIONAL NORMALIZED RATIO INDICATES INCREASED ABILITY TO FORM BLOOD CLOT

PTT

HIGHER PTT INDICATES DECREASED ABILITY TO FORM BLOOD CLOT

LOWER PTT INDICATES INCREASED ABILITY TO FORM BLOOD CLOT

FIBRINOGEN

HIGHER VALUES OF FIBRINOGEN INDICATES INCREASED ABILITY TO FORM BLOOD CLOT

LOWER VALUES OF FIBRINOGEN INDICATES DECREASED ABILITY TO FORM BLOOD CLOT

D-DIMER

HIGHER VALUES OF D DIMER INDICATES INCREASED ABILITY TO FORM BLOOD CLOT

LOWER VALUES OF D DIMER INDICATES DECREASED ABILITY TO FORM BLOOD CLOT

COAGULATION FACTOR 13

HIGHER VALUES OF C FACTOR 13 INDICATES INCREASED ABILITY TO FORM BLOOD CLOT

LOWER VALUES OF C FACTOR 13 INDICATES DECREASED ABILITY TO FORM BLOOD CLOT

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