Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

Using the oxygen dissociation curve, determine the saturation % of hemoglobin in

ID: 3476761 • Letter: U

Question

Using the oxygen dissociation curve, determine the saturation % of hemoglobin in the lungs 100 80 9 60 E 50 20 ! 10 0 20 40 60 80 100 mm Hg 0 8 12 kPa Partial pressure of O, in blood Using the oxygen dissociation curve, determine the saturation % of hemoglobin in th lungs Blood leaving the lungs carries 20 ml O2 / 100 ml. If there is no Bohr shift, and the oxygen pressure in the tissues is 35 mm Hg, how much oxygen (in ml O2 / 100 ml) is unloaded to the muscles? With the Bohr shift, how much is unloaded (in ml 02/100 ml)? 5.

Explanation / Answer

The Bohr effect states that the affinity of haemoglobin to oxygen is inversely proportional to acidity and carbon dioxide concentration.

4) In the absence of Bohr effect, 70% oxygen is bound to the haemoglobin. So, 6 ml of O2/100 ml is unloaded to the tissues.

5) In the presence of Bohr effect, the haemoglobin affinity for oxygen decreases to 50%. So, the amount of oxygen unloaded in tissues become 10 ml of O2/100 ml.