1. Consider a cell with the following inside and outside ionic concentrations: I

Question

1. Consider a cell with the following inside and outside ionic concentrations: Ion In (mM) Out (mM) Nernst Nat 150 90.1 mV K- 145 2.5 -107.6 mV 25 -42.6 mV a. Assuming the resting membrane potential is -120 mv, and the cell uses Na and K' for its action potential, what would be the maximum voltage possible at the peak of the action potential? Indicate the DIRECTION of ion movements during the depolarization as well as the repolarization phases of the action potentials b. Would this cell have an afterhyperpolarization if it used Na and K? Yes or no

Explanation / Answer

1) a) The maximum voltage possible at the peak of action potential is 90 mV. During depolarisation, there will be an influx of sodium ions and during repolarization, there will be an efflux of potassium ions.

b) The cell will have a hyperpolarization phase following repolarization due to continuous leakage of potassium ions from the cell.

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