1.On the top plot, label the following values/areas. -Resting membrane potential
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Question
1.On the top plot, label the following values/areas. -Resting membrane potential -Threshold voltage -Sub threshold voltage m 70 pv 2. On the second plot label: axon.soma vi.5 -Na Curve -K Curve 20 10 15 .30 3. On the Third Plot label -Na Curve -K Curve 80 mres d 025 Siemens/em? axprtsoma gna na Why does one curve have positive values while the other has negative? 0013 0.005 10 15 20 0,005 0.5 mVem2 0.3 0.1 ina il leak 4. On the Fourth Plot label: 10 15 20 -Na activation -Na inactivation -K activation Absolute refractory 0.3 0.5 Cuve Period Im na 0.8F 0.6 0.4 0.2 -Relative refractory Period na.nk What governs the absolute and relative refractory periods? 500 300 100 100 300 -500 - axon ccli Why are they important? 10 15Explanation / Answer
Since the labelling of curves is already indicated i shall explain the other questions:
For Q.1,2&3: There is extrusion of 3 sodium ions & influx of 2 potassium ions during generation of neuronal membrane potential gradient. This results in positive & negative curves.
Q.4: Absolute refractory period is the time between the axon stimulation & period after the peak curve. Relative refractory period follows absolute refractory period.
Absolute refractory period is governed by sodium channel closure & relative refractory period is governed by potassium efflux causing hyperpolarization.
Importance of absolute refractory period is that neuron/axon cannot be stimulated to generate secondary action potential due to inactivation of sodium channels & we can know the maximum peak of action potential achieved during stimulus from resting state of neuron.
During relative refractory state, very strong stimulus is required to achieve secondary action potential owing to reactivation of sodium channels maintained by potassium efflux.
These are possible explanations for the above queries.
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