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In randomized, double-blind clinical trials of a new vaccine, infants were rando

ID: 3363958 • Letter: I

Question

In randomized, double-blind clinical trials of a new vaccine, infants were randomly divided into two groups. Subjects in group 1 received the new vaccine while subjects in group 2 received a control vaccine. After the second dose, 128 of 474 subjects in the experimental group (group 1) experienced drowsiness as a side effect. After the second dose, 109 of 601 of the subjects in the control group (group 2) experienced drowsiness as a side effect. Does the evidence suggest that a higher proportion of subjects in group 1 experienced fever as a side effect than subjects in group 2 at the -010 level of significance? Verify the model requirements. Select all that apply. The sample size is more than 5% of the population size for each sample. The data come from a population that is normally distributed. A. B. c. D. E. F. n1p1 (1-p.) 210and n2P2(1-p2) 210 The samples are dependent. The sample size is less than 5% of the population size for each sample The samples are independent.

Explanation / Answer

SOL:

The given below are conditions to be checked for diff in proportions

Success/Failure condition:

the expected number of successes and faillures >10

n1p1^,n1(1-p1^) both should be greater than 10 and also

n2p2^,n2(1-p2^) both should be greater than 10

10% condition:

each sample is less than 10% of the population

Randomization:

the sample obtained was through random sample techniques

sampling distribution of p^ is nearly normal.

sample observations are independent.

COMING TO THE ANSWERS GIVEN IN CHOICES:

OPTION B

OPTIONC

OPTIONF

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