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According to a commentary in the Journal of the American Medical Association, \"

ID: 3359137 • Letter: A

Question

According to a commentary in the Journal of the American Medical Association, "Thus, vitamin E enters the category of therapies that were promising in epidemiologic and observational studies but failed to deliver in adequately powered randomized controlled trials. As in other studies, the 'healthy user' bias must be considered, i.e., the heathy lifestyle behaviors that characterize individuals who care enough about their health to take various supplements are actually responsible for the better health, but this is minimized with the rigorous trial design."

What are the explanatory and confounding variables in the study above?

A) Explanatory: taking vitamin E; confounding: healthy lifestyle behaviors

B) Explanatory: healthy lifestyle behaviors; confounding: taking other various supplements

C) Explanatory: taking other various supplements; confounding: taking vitamin E

D) Explanatory: taking other various supplements; confounding: healthy lifestyle behaviors

E) Explanatory: healthy lifestyle behaviors; confounding: taking vitamin E

F) Explanatory: taking vitamin E; confounding: taking other various supplements

Explanation / Answer

Here,

Confounding variable is the lifestyle of health people since it is indirectly affecting the results obtained by taking Vitamin E.

Hence,

Explanatory: taking vitamin E; confounding: healthy lifestyle behaviors

Option A is correct.

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