A clinical microbiology compared the frequency of isolation of DNA hybridization

Question

A clinical microbiology compared the frequency of isolation of DNA hybridization probe to a culture method for the sexually transmitted bacterium Neisseria Gonorrhaeae. The frequency of isolation from clinical specimens was historically 10%. The lab ran 100 splits samples, and the results are presented in the table below.
1a)Calculate the positive Predictive Value? 1b) Calculate the negative Predictive Value? 3- A clinical microbiology laboratory compared the frequency of isolation of DNA hybridization probe to a culture method for the sexually transmitted bacterium Neisseria gonorrhaeae. The frequency of isolation from clinical specimens was historically 10%. The lab ran 100 split samples, and the results are presented in the table below. (20 pts) Table. Comparison of the Distribution of Negative and Positive Results for the DNA Probe and Culture Methods. Culture Results DNA Probe Results Positive Negative Positive Negative 1) Calculate the positive predictive value? 2) Calculate the negative predictive value?

Explanation / Answer

Positive Predictive value = True positive / Total positive

= 9/(9+1)

= 0.9

Negative Predictive Value = True negative / Total Negative

= 88/(88+2)

= 0.978

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