Is this proper reasoning for below question? DNA replication from the ORI point
ID: 319184 • Letter: I
Question
Is this proper reasoning for below question?
DNA replication from the ORI point on bacterium can proceed bidirectionally, so divide genome size by 2. --> 6*10^6 /2 base pairs
3*106 base pairs is 6*106 nucleotides, so to replicate the entire genome it would take 6*10^6 nucleotides divided by 1000 nucleotides/second --> 6000s
A bacterium has a genome size of 6*106 base pairs. There is one Origin of Replication (ORI) and each DNA polymerase catalyzes the addition of 1,000 nucleotides/second. How much time is needed to replicate the entire genome of the bacterium?
Explanation / Answer
Ans: Bacteria whose genome size is 6*106 bp, typically have a single origin of replication in a circular chromosome. With fork speeds of up to 1000 nucleotides per second, they can replicate their genome in less than an hour.
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