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An article in the Journal of the American Medical Assocation described an experi

ID: 3182512 • Letter: A

Question

An article in the Journal of the American Medical Assocation described an experiment to investigate the effect of four treatments on various body characteristics. In this double-blind experiment, each of 58 female subjects age 65 or older was assigned at random to one of the following four treatments:

1) P + P: placebo "growth hormone" and placebo "steroid"
2) P + S: placebo "growth hormone" and the steroid estradiol
3) G + P: growth hormone and placebo "steroid"
4) G + S: growth hormone and the steroid estradiol

The change in body fat mass was measured over the 26-week period following the treatments. Using the information provided above and in the partial table below, complete the ANOVA table (use 2 decimals for your SS, MS, and F value answers).

Source of Variation df Sum of Squares Mean Square F Treatment Error 2.37 X Total 201.41 X X

Explanation / Answer

Here Total df = n - 1 = 58 - 1 = 57

df(T) = k - 1 = 4 -1 = 3

df(E) = n - k = 58 - 4 = 54

MS = SS/df

F = MST/MSE

Source of Variation df SS MS F Treatment 3 73.43 24.4767 10.3277 Error 54 127.98 2.37 Total 57 201.41
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