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An article in the Journal of the American Medical Assocation described an experi

ID: 3155660 • Letter: A

Question

An article in the Journal of the American Medical Assocation described an experiment to investigate the effect of four treatments on various body characteristics. In this double-blind experiment, each of 63 female subjects age 65 or older was assigned at random to one of the following four treatments:

1) P + P: placebo "growth hormone" and placebo "steroid"
2) P + S: placebo "growth hormone" and the steroid estradiol
3) G + P: growth hormone and placebo "steroid"
4) G + S: growth hormone and the steroid estradiol

The change in body fat mass was measured over the 26-week period following the treatments. Using the information provided above and in the partial table below, complete the ANOVA table (use 2 decimals for your answers).

Source of Variation df Sum of Squares Mean Square F Treatment Error 2.6 X Total 223.42 X X

Explanation / Answer

df treatments = 4-1 = 3

df error = 63-4 = 59

df total = 59+3 = 62

SSerror = 2.6 * 59 = 153.4

SS treatment = 223.42 - 153.4 = 70.02

MS treatment = 70.02 / 3 = 23.34

F = 23.34 / 2.6 = 8.977

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