32. Since the first nucleotides cannot be linked in a newly synthesized strand i

Question

32. Since the first nucleotides cannot be linked in a newly synthesized strand in DNA replication is required. a DNA primer a. b. DNA polymerase c. ligase d. an RNA primer e. helicase 33. Each unit of a nucleic acid consisting of a sugar, attached phosphate group, and base is a a. nucleolus b. nucleotide C. nucleosome d. histone e. genetisome 34. Prior to the production of recombinant insulin, insulin obtained from cows and pigs were given to patients. Some of the problems faced by this treatment was a. b. in some humans, it induced antibody production c. it reduces the weight of patients d. loss of memory power the insulin was not active

Explanation / Answer

32.b ; DNA Polymerase : DNApolymerases can only add new nucleotides to an existing strand of DNA.

33.b : Nuucleotide : A nucleotide consists of a nitrogenous base, a sugar (ribose or deoxyribose) and one to three phosphate groups. A nucleoside consists of a nitrogenous base covalently attached to a sugar (ribose or deoxyribose) but without the phosphate group. 34.b : In some huumans it induced antibody productin.

The composition of bovine and porcine insulin are slightly different from the human insulin. The patient's immune system produced antibodies against animal origin insulin and these antibodies induced inflammatory response at injection sites.of injection. Antibodies also neutralised the biological action of animal origin insulin.   

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