The neural tube is an embryonic structure that develops into the brain and spina

Question

The neural tube is an embryonic structure that develops into the brain and spinal cord. Neural tube defects (NTD’s) are influenced by both genetic and environmental factors. The empiric risk for the defect to occur in a previously unaffected family is less than 1%. However, the risk of recurrence increases about 3% if one child is affected, and another 3% if a parent or a second child is also affected.
The estimated NTD recurrence risk to the pregnancy shown in the following pedigree is _________.

Explanation / Answer

7% [ (1% due to the empiric risk for the defect to occur in a previously unaffected family)+(3% recurrence risk on first child)+(3% recurrence risk is increased on? the birth of second child)]

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