1a) explain the difference between penetrance and expressivity. b) c) Please hel

Question

1a)
explain the difference between penetrance and expressivity.

b)

c)

Please help i have only 50 minutes

Question 2 (2 points) The neural tube is an embryonic structure that develops into the brain and spinal cord. Neural tube d influenced by both genetic and environmental factors. The empiric risk for the defect to occur in a previously unaffected family is less than 1% However, the risk of recurrence increases about 3% if one child is affected, and another 3% ifa parent or a second child is also affected The estimated NTD recurrence risk to the pregnancy shown in the following pedigree is efects (NTD's) are ob Save

Explanation / Answer

(a) Penetrance is the percentage of indiviuals that shows a particular phenotype among those capable of shown it.
Expressivity is the phenomenon of a particular gene may produce different degrees of expression in different individuals
?(B) total recurrence risk will be 7% ( not affected parents (1%)+ 2 elder sibllings afeected (3+3)% )
(C) 1.biomagnification
?    2.gene flow
?    4. evolution
(D)
?wife's mother is AB and father is O therfore she have to be a hetrozygous that is her blood group genotype will be Ia?i
?and now cross between this and her husband blood group O will be as follows:

?now probablity of blood groups are as follows
A - 1/4
?B - 0
?AB- 0
O - 3/4

I?a i i Ia?i
A blood group ii
o blood group i ii
?o blood group ii
o blood group

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