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1a) Restriction enzymes_______and______ would be used to clone a segment of frog

ID: 68468 • Letter: 1

Question

1a) Restriction enzymes_______and______ would be used to clone a segment of frog DNA.

1b) The size of the recombinant plasmid is _________bp.

1c) The recombinant plasmid when transformed into E. coli confers resistance to which of the following antibiotics:

tetracycline only

ampicillin only

beta-galactocillin only

ampicillin and beta-galactocillin

ampicillin and tetracycline

tetracycline and beta-galactocillin

1d)

The recombinant plasmid map has many restriction sites. Determine the base pair position of each of the following sites in the recombinant plasmid map:

Restriction Enzyme Vector Position Recombinant Position XhoI 240 Answer DraI 935 Answer XmaIII 2780 Answer SacI 3150 Answer

Explanation / Answer

1A. RsaI and ECoRI for cloning the frog DNA

1B. size of recombinant plasmid: 4315bp

1C. ampicillin only. As the Tetr is disturbed due to cloning

1D. DraI= 2100bp

XhoI= 240bp

SmaIII= 3945

SacI= 4315

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