Refer to Figure 1: Which of the following is (are) examples if positive selectio

Question

Refer to Figure 1: Which of the following is (are) examples if positive selection. Choose all the correct answers. A. Use of an anti neutrophil antibody to eliminate neutrophils from a stem cell preparation B. Use of a B cell marker to increase the amount of B cells harvested from a sample C. Use of natural killer cell antibody to harvest these cell for a patient Circulating Blood Cells T b cell marker Google 5 x board.com/b webdav pid 1641208 dit content rid 3645712 1/courses/R2.201720MWork Info for Questions 1-2: In an experiment to enrich hematopoietic stems, p selection was done to recov isolate HSC as shown in the cartoon in Figure 1. Unfortunately, after microscopic examination, it was found that there are some cells with different morphologies than was expected. GE ON React with Negative selection FI antibodies against cells that differentiation antigens (lineage) markers Positive selection for cells that against Sca-1 express stem cell markers Sca-1 FIGURE 1

Explanation / Answer

B. Use of a B cell marker to increase the amount of B cells harvested from a sample

because The process of Positive selection involves the process of signaling to happen through the antigen receptor for the cell in order to survive. This happens with an increase in B cells as the B cells are positively selected whenever the pre-B receptor binds its ligand to it.

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