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Based on our knowledge of weak molecular bonds and how they make up the structur

ID: 315716 • Letter: B

Question

Based on our knowledge of weak molecular bonds and how they make up

the structure of important macromolecules in the cell, hypothesize which of the following three molecules: proteins, mRNA or genomic DNA, are most stable or most labile under the following conditions:

Give stability in terms of >, <, >=, <= or =.

For example, if you think X will be more stable than Y and Z, which are equally stable,

then write: X > Y=Z

Conditions: 1) Heat shock (ie a short exposure to extreme heat)

2) Exposure to phenol (a completely hydrophobic solvent)

Explanation / Answer

for condition 1

mRNA >proteins=genomic DNA

because MRNA is a family of RNA molecules that help to convey genetic information from DNA to the ribosome, On heating they are toughest to break due to strong bonds unlike present in proteins and genomic DNA.

for condition 2

on expose to phenol

proteins=genomic DNA >mRNA

because phenol acts on proteins and genomic DNA due to the presence of hydophobic bond unlike in mRNA

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