Most alleles detected by a single-locus RFLP/VNTR probe differ from each other b

Question

Most alleles detected by a single-locus RFLP/VNTR probe differ from each other by a

point mutation in the flanking region.

copy-number mutation in the repeat region.

point mutation in the repeat region.

Digestion of human genomic DNA with a restriction enzyme followed by gel electrophoresis results in

destruction of the DNA.

a banding pattern that can be used as a DNA fingerprint.

a single-locus VNTR.

hybridization of the DNA to a radioactive probe.

a “smear” of millions of DNA fragments of all possible sizes.

point mutation in the regulatory region.

copy-number mutation in the flanking region.

Explanation / Answer

1.Answer b: copy number in the repeat region .Most allele detected by a single locus RFLP probe differ from each other copy number mutation in the repeat region

2 Answer b: In DNA fingerprinting restriction enzyme which cut DNA into thousand pieces these pieces of DNA separate by process called gel electrophoresis

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