To check pain-relieving medications for potential side effects on blood pressure
ID: 3128141 • Letter: T
Question
To check pain-relieving medications for potential side effects on blood pressure, it is decided to give equal doses of each of four medications to test subjects. To control for the potential effect of weight, subjects are classified by weight groups. Subjects are approximately the same age and are in general good health. Two subjects in each category are chosen at random from a large group of male prison volunteers. Subjects’ blood pressures 15 minutes after the dose are shown below. Research question: Is mean blood pressure affected by body weight and/or by medication type?
Systolic Blood Pressure of Subjects (mmHg)
Fill in the missing data. (Round your table of means values to 1 decimal place, SS and F values to 2 decimal places, MS values to 3 decimal places and p-value to 4 decimal places.)
Factor 2 (Medication)
Perform Tukey multiple comparison tests. (Input the mean values within the input boxes of first row and input boxes of the first column. Round your t-values and critical values to 2 decimal places and other answers to 1 decimal place.)
Tukey simultaneous comparison t-values (d.f. = 12)
Tukey simultaneous comparison t-values (d.f. = 12)
To check pain-relieving medications for potential side effects on blood pressure, it is decided to give equal doses of each of four medications to test subjects. To control for the potential effect of weight, subjects are classified by weight groups. Subjects are approximately the same age and are in general good health. Two subjects in each category are chosen at random from a large group of male prison volunteers. Subjects’ blood pressures 15 minutes after the dose are shown below. Research question: Is mean blood pressure affected by body weight and/or by medication type?
Explanation / Answer
Sol) From Excel
Anova: Two-Factor With Replication SUMMARY M1 M2 M3 M4 Total Under 1.1 Count 2 2 2 2 8 Sum 264 281 277 252 1074 Average 132 140.5 138.5 126 134.25 Variance 32 24.5 24.5 32 53.35714 1.1 to 1.3 Count 2 2 2 2 8 Sum 285 279 280 267 1111 Average 142.5 139.5 140 133.5 138.875 Variance 40.5 40.5 128 0.5 42.41071 1.3 to 1.5 Count 2 2 2 2 8 Sum 296 306 298 283 1183 Average 148 153 149 141.5 147.875 Variance 2 32 8 0.5 25.55357 Total Count 6 6 6 6 Sum 845 866 855 802 Average 140.8333 144.3333 142.5 133.6667 Variance 67.76667 64.66667 57.9 54.66667 ANOVA Source of Variation SS df MS F P-value F crit Sample 768.0833 2 384.0417 12.62603 0.001117 3.885294 Columns 392.3333 3 130.7778 4.299543 0.028122 3.490295 Interaction 91.91667 6 15.31944 0.503653 0.794342 2.99612 Within 365 12 30.41667 Total 1617.333 23Related Questions
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