8. Autografts will be rejected only rarely because of all but which of the follo

Question

8. Autografts will be rejected only rarely because of all but which of the following? A They are from the same individual. B. They are MHC matched. C. They do not trigger an immune response. D. They have Th17 cells E. All of the above. 79. Insulin-dependent diabetes: A. usually shows juvenile onset. B. is more common in men that in women. C. interferes with fat metabolism. D. seems to be triggered by antibodies. E. None of the above. 80. Role of class II MHC proteins on donor cells in graft rejection A. They are the receptors for interleukin-2, which is produced by macrophages when they Attack the donor cell:s They are recognized by T helper cells, which activate cytotoxic T cells to kill the donor cells B. D They induce IgE which mediates graft rejection 81.The tuberculin(tuberculosis) reaction is an example of which type of hypersensitivity A. Type I B. Type II C. Type III D. Type of the above E. None of the above 82. Because T cells are important in graft rejection, nude mice, which lack a thymus: A. will reject grafts the same as wild-type mice. B. will reject grafts more vigorously than wild-type mice. C. will not reject grafts since they lack T cells. D. will not reject grafts since they lack B cells. E. will not reject grafts because of peripheral tolerance 83. Which of the following may explain why women may be at higher risk for some autoimmune disorders? A. High IgM and CD4 levels B. High IgM and CD8 levels C. Low lgM and Low CD8 levels D. None of the above

Explanation / Answer

78. Correct answer:- (E) all of the above
Explanation:- autografts are rarely rejected because- they are from the same individual.
- they are MHC matched.
- they not trigger immune response.

79. Correct answer:- (A) usually shows juvenile onset.
Explanation:- insulin dependent Diabetes mellitus is also called type 1 or juvenile onset.

80. Correct answer:- (B)They are recognized by helper T cells, which then activate cytotoxic T cells to kill the donor cells.
Explanation:- In acute graft rejection donor’s class II MHC proteins are recognized by host’s T helper cells. These T helper cells in turn activate Cytotoxic T cell, which kill the donor’s cells. Therefore, acute graft rejection mimics delayed hypersensitivity reaction.

81. Correct answer:- (D) type IV
Explanation:- tuberculin Reaction is an example of delayed or type IV hypersensitivity reactions.

82. Correct answer:- (C) will not reject grafts since they lack T cell.

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