Name Bios 220 exam 3 6: Levofloxacin is a broad-spectrum antibiotic that inhibit
ID: 303193 • Letter: N
Question
Name Bios 220 exam 3 6: Levofloxacin is a broad-spectrum antibiotic that inhibits DNA gyrase. What is the most likely reason it can kill bacteria A. It blocks prokaryotic DNA replication by preventing melting of the DNA double helix at the replication fork B. It blocks prokaryotic DNA replication by preventing unwinding of the super coils in the DNA double helix C. It interferes with prokaryotic DNA replication by preventing fusion of Okazaki fragments D. it blocks prokaryotic transcription by preventing unwinding of the DNA double helix during transcriptional initiation E. it blocks prokaryotic transcription by preventing unwinding of the DNA double helix during transcriptional elongation Use this information for the next two multiple choice questions: You are working with Marshal Nirenberg, and you synthesize a polyribonucleotide containing equal amounts of randomly positioned adenine and uracil bases The codons for phenylalanine are UUU and UUC . The codons for isoleucine are AUU, AUC, and AUA. 7: What proportion of triplets will encode phenylalanine B. 1/8 C. 1/4 E. 3/4 8: What proportion of triplets will encode isoleucine B. 1/8 C. 1/4 D. 1/2 E. 3/4 9: Which of the following constitutes the primary structure of a protein? A. The folding of a polypeptide chain B. The linear sequence of amino acids in a polypeptide chair C. The polypeptide chains stacked on top of each other D. A pleated sheet E. Several polypeptide subunitsExplanation / Answer
6. levofloxacin inhibits DNA gyrase-
it blocks prokaryotic DNA replication by preventing unwinding of the supercoils in the DNA double helix.
it causes positive supercoiling in excess.as DNA gyrase comprises of 2 A and 2 B subunits.levofloxacin binds to the A subunit and restrict the function of gyrase.
7. 3/4
8. 1/2
9. linear sequence of amino acids in a polypeptide chain.
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