33. Consider the figure below. Explain what the difference is among the three di
ID: 301113 • Letter: 3
Question
33. Consider the figure below. Explain what the difference is among the three different types of mice shown. There are genes on chromosome eleven that are involved in the development of the placenta. Explain why the results of this experiment make sense when considered in evolutionary terms Both copitts from mother Mouse smaller than nomai. One copy from sach parent. Normal mouse. Both copies from father Mouse larger than normal. Source of chromosome 11 Figure 8.1 Bruce Cattanach created genetically modified mice, in which he could control how they inherited a particular region of chromosome I1. he middle mouse inherited one copy from each parent. Mice which inherited both copies from their mother were smaller than this normal mouse. In contrast, mice which inherited both copies from their father were larger than normal. Image source: Carey, N., 2012. The epigenetics revolution. Columbia University Press, New York, NY.Explanation / Answer
As per the figure shown, major difference lies in the size of the mice. In mice and humans,there is a pair of homologous chromosomes for each gene, one of maternal and paternal source each. However, there may be different alleles of these genes in both the parents. Thus depending on the genes inherited during zygote formation, the offspring may show maternal or paternal (homozygous) or heterozygous trait.
As per the experiment, chromosomally balanced mice with homologous chromosomes derived from either of the parent can be easily reproduced by performing Robertsonian translocations. Such Robertsonian translocations may produce maternal and paternal disomy for chromosome 11. As observed some offsprings may grow smaller in size (as mother), bigger in size (as father) or heterozygote (intermdeiate). If such translocations occur naturally then it would be inherited in further generations. Everytime during fertilization, different alleles from parents would be inherited thereby resulting in evolution in the trait.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.