a Dep a rtment of Pedi a trics, St a nford Hospit a l, St a nford, C a liforni a

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a Department of Pediatrics, Stanford Hospital, Stanford, California
b HopeLab Foundation, Redwood City, California
c Health Research Center, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, West Virginia
d Department of Epidemiology and Biostatistics, School of Medicine, and San Antonio Cancer Institute, University of Texas Health Science Center, San Antonio, Texas

OBJECTIVE. Suboptimal adherence to self-administered medicationsis a common problem. The purpose of this study was to determinethe effectiveness of a video-game intervention for improvingadherence and other behavioral outcomes for adolescents andyoung adults with malignancies including acute leukemia, lymphoma,and soft-tissue sarcom

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