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A large study was conducted to test the effectiveness of anexperimental blood th

ID: 2919158 • Letter: A

Question

A large study was conducted to test the effectiveness of anexperimental blood thinner, clopidogrel, in warding off heartattacks and strokes. The study involved 19185 patients who hadsuffured hear attacks, strokes, or pain from clogged arteries. Theywere each randomly assigned to take either aspirin or clopidogrelfor a period of 1 to 3 years. Of the patients taking aspirin, 5.3%suffered heart attacks, strokes, or death from cardiovasculardisease; the correponding percentage in the clopidogrel patientswas 5.8% The article states that each patient was randomly assigned toone of the two medications. Explain how you could use the randomnumber table to make these assignments. A large study was conducted to test the effectiveness of anexperimental blood thinner, clopidogrel, in warding off heartattacks and strokes. The study involved 19185 patients who hadsuffured hear attacks, strokes, or pain from clogged arteries. Theywere each randomly assigned to take either aspirin or clopidogrelfor a period of 1 to 3 years. Of the patients taking aspirin, 5.3%suffered heart attacks, strokes, or death from cardiovasculardisease; the correponding percentage in the clopidogrel patientswas 5.8% The article states that each patient was randomly assigned toone of the two medications. Explain how you could use the randomnumber table to make these assignments.

Explanation / Answer

Hints: Label: If we use random number table to make these assignments 1) Each entry in the table is equally likely to be any of the 10digits 0 through 9. 2) The entries are independent of each other. That is, knowledgeof one part of the table gives no information about any otherpart. We must label the patients as 00001,00002,......, 19185. Random Table: To choose an SRS, read from Table successivegroups of digits of the length you used as labels. Your samplecontains the individuls whose labels you find in the table.
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