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An article in Cancer Research \"Analysis of litter-matchedtime-to-response data,

ID: 2914633 • Letter: A

Question

An article in Cancer Research "Analysis of litter-matchedtime-to-response data, with
modification for recovery of interlitter information," (1977,Vol.37, pp.3863-3868) tested the
tumorigenesis of a drug. Rats were randomly selected from littersand given the drug. The
times of tumor appearance were recorded as follows:
101, 104, 104, 77, 89, 88, 104, 96, 82, 70, 89, 91, 39, 103, 93,85, 104, 81, 67, 104, 104,
104, 87, 104 ,89, 78, 104, 86, 76, 103, 102, 80, 45, 94, 104, 104,76, 80, 72, 73.
Calculate a 95% confidence interval on the standard deviation oftime until a tumor
appearance. Check the assumption of normality of the population andcomment on the
assumptions for the confidence interval.

Explanation / Answer

This is incorrect. you have to use the chi squared distributionsince we are looking for the std dev. z values cannot be used inthis case. Will rate lifesaver to the person who can confirm thisand do the problem correctly.

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