Ls4203_class test_2017 please answer only question no.4. (2+1+1+1=5marks) How ma

Question

Ls4203_class test_2017

please answer only question no.4. (2+1+1+1=5marks)

How many molecules of ATP will be produce by the complete aerobic oxidation of the followin compound? With explanation. How cholesterol biosynthesis is regulated? Explain the mode of action of statin group of drugs? What are the important biomolecules formed from Isopentenyl pyrophosphate? And what are the important biomolecules formed from cholesterol? 3 What are the needs of Cytochrome p-450 in the fatty acid synthesis? Give example of two essential fatty acids? Is arachidomic acid belongs to o3 or o6 fatty acids family? What is the function of Lipoxygenase? Discuss the mode of action of Aspirin. 4. What is glycerogenesis? How glycerogenesis regulate Triacylglycerol cycle? In which organ glycerogenesis is taking place and in which organ triacylglycerol cycle taking place? 2+1+1+1-5

Explanation / Answer

When the glucose are react with each other and followed the metabolic path it produces a compound namely glycerol 3-phosphate or triglyceride that metabolic pathway is known as gluconeogenesis. The reaction or the process generally takes place to generate the glycerol 3-phosphate is known as the glycolysis but when glucose concentration decreases in the reactice compound then then it undergoes to another pathway which is known as glyceroneogenesis.Glyceroneogenesis can be detected in tissue of adipose and also in liver.

Triacylglycerol cycle extracted metabolites which are present in it and also known as glutamate are used as a reactant glucose for the process of glyceroneogenesis, the products which are formed by the process of glyceroneogenesis can observe the flux ehich is due to the regulator of the Triacylglycerol cycle so regulation of Triacylglycerol cycle can be known or calculated by product inhibitors and substrate presence. This cycle would slow down when excess product is present in the environment or deficient of substrate such as

Adenosine diphosphate

Nicotinamide adenine dinucleotide

.Glyceroneogenesis and Triacylglycerol cycle is observed or detected in the following organs

1). ADIPOSE TISSUES

2) LIVER

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