Map Q: Glutamine L Leucine E Glutamate b) What are the three-letter abbreviation
ID: 282255 • Letter: M
Question
Map Q: Glutamine L Leucine E Glutamate b) What are the three-letter abbreviations for the amino acids? Q: Gln L: Leu E: Glu )What is the overall charge of the most abundant tripeptide species at neutral pH (pH 7.0)? Numberrt (c) is incorrect. lonizable groups are protonated below their pKa values.The amino- terminal end of a peptide has a pKa of-8. The carboxyl end has a pKa of -3. In addition, one of the side chains is ionizable. The pKa of the side chain is 4.1. Is it Once you have determined the charges on the amino end, the carboxyl end, and the d) At physiolos charged or uncharged at pH 7.0 Q: polar ionizable side chain, add the charges to determine the overall charge on the tripeptide e) What is the overall charge of the most abundant tripeptide species below pH 1.0 continued below. Number Enter your answer as a whole number. What is the overall charge of the most abundant tripeptide species at pH 11.5? Number Enter your answer as a whole number.Explanation / Answer
b.Three letter abbreviations for the amino acids:
Q.Gln:Glutamine
L.Leu:Leucine
E.Glu:Glutamic acid
(Note:Q,L,E are the one latter abbreviations of the above mentioned amini acids).
c.Overall charge of the most abundant tripeptide species at neutral pH(pH 7.0)
Taking Ser-Val-Arg as most abundnat tripeptide species(most abundnat proteins in vertebrates).
A compound,especially with neumerous functional groups,can have a lot of pKa and pKb charges.These are the individual acidic(pKa) and basic (pKb) charges of each functional group in the compound.These charges affect one another due to electrostatic attractions.When you want to find the net charge or the overall charge of the compound,you have to test it by using a pH meter.If the pH you get is 7,Then it is neutral.The range of pH between 1 to 14.pH's 1 to 6 are acidic,and pH's 8 to 14 are basic.The neutral pH is at pH 7 like pure water.That means that overall charge is 0.
e.The overall charge of the most abundant tripeptide species below pH 1.0
At pH=1,
NH3-Ser-Val-Arg-COOH
+1-X-X-+1-0
Thus,the net charge is 2.
At pH=11,
NH2-Ser-Val-Arg-COOH
0-X-X-+1--1
Thus the net charge is 0.
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