Map Sapling Learning macmillan learning Answer the following seven questions (a

Question

Map Sapling Learning macmillan learning Answer the following seven questions (a through g) based upon a tripeptide sequence with the following amino acids (one-letter symbols are given) Q L E a) What are the full names of the amino acids? Spelling counts, but capitalization does not For an acidic amino acid, assume it is ionized and use the-ate ending instead of - ic acid b) What are the three-letter abbreviations for the amino acids? L: E: c) What is the overall charge of the most abundant tripeptide species at neutral pH (pH 7.0)? Number Enter your answer as a whole number d) At physiological pH, what is the best description of the chemical properties of the side chain (R group)? Q Select answer L Select answer E Select answer e) What is the overall charge of the most abundant tripeptide species below pH 1.0? continued below

Explanation / Answer

a) Q- Glutamine L- Leucine E- Glutamate

b) Q- Gln L- Leu E- Glu

c) The overall charge of the most abundant tripeptide species at neutral pH is +1

d) Q- Biosynthesis of proteins L- Protein synthesis E- acts as a intermediate in citric acid cycle.

e) At pH 1 or less than pH 1 the carbonyl group present on glutamate is protonated and gives a net charge of +2

f) At pH above 9 ie at 11.5 the amino groups will disassociate and gives a net charge of +1and -1 in a 50:50 ratio. Where half posses +1 and other half with-1 charge.

g) In the amino acids the side chains are capable of forming H-bonds with water. The water molecules may accept or donate 2 H atoms. And hence the intermolecular forces between the side chain and water are hydrogen bonds.

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