l Verizon 11:03 AM 76% KBack Assignment 2 (due 6/26) Question 6 Answer saved Gra

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l Verizon 11:03 AM 76% KBack Assignment 2 (due 6/26) Question 6 Answer saved Graded out of 6.000 An important question in the early 2000s was whether drug or device therapy to stop (or prevent) cardiac arrhythmias could prevent sudden cardiac death in patients with moderate heart failure but no history of life-threatening arrhythmias. (Cardiac arrhythmias are essentially an electrical problem in the heart, whereas heart failure is more of a mechanical problem.) The Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) randomized patients with moderate heart failure in a 1:1:1 ratio to drug (amiodarone), placebo, or implantable cardioverter defibrillator (ICD) device. The primary outcome of the trial was death from any cause, and the primary comparison groups were amiodarone vs placebo and ICD vs placebo. Participants and providers were not blinded to whether the participant was receiving device therapy or oral therapy, but for those randomized to oral therapy, participants and providers were blinded to whether the participant was receiving placebo or amiodarone. (Optionally, you can read more hout this trial here

Explanation / Answer

ans-1 the possible reason behind this decision should the requirement of random sampling for a better interpretation of the result which might not be possible with the help of selective sampling. the other reason may be that the investigators may want to observe the effect of both type of people first who take placebo and amiodrane.

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