Deinococcus radiodurans is probably the world’s toughest bacterium (first discov
ID: 278135 • Letter: D
Question
Deinococcus radiodurans is probably the world’s toughest bacterium (first discovered growing in ground meat that had been “sterilized” by radiation), able to withstand doses of ionizing radiation ~3000 times greater than those that are lethal to humans. It was also discovered that D. radiodurans has a particularly large number of genes that encode for DNA repair proteins and multiple (4 to 10) copies of its closed circular genome per cell. It has been hypothesized that these multiple dsDNA copies of the genome are aligned and stacked like coins. How would this spatial arrangement help D. radiodurans efficiently repair its DNA?
Explanation / Answer
Dienococcus radiodurans is the world's toughest bacterium recorded in Guinness world record. It may tolerate upto 5000 grays. They can tolerate very high radiation. They bear genetic material tightly arranged called toroid. During damage there takes two steps. In first step single strands are annealed and then dsDNA brak take place to repair DNA and joined by homologous recombination repair is joined.
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