11. You notice an extra chromosome in a patients karyotype- which of these condi
ID: 276799 • Letter: 1
Question
11. You notice an extra chromosome in a patients karyotype- which of these conditions might be caused by this trisomic addition? E Atas Syndrome B) Parkinsons Disease C) Huntingtons Disease D) Turner Syndrome All of the above are possible 12. Which of the following represents the best possible (not ikely to be random) ' value from a BLAST result? A) 0.15 B)6.1 C)0.0 D)-150 E)-24 13. You have pipetted an unknown volume of water onto the scale, which reads: What volume have you transferred? A) 87.3 g B) 873 g C) 87.3 uL D) 873 uL E) 873 mg 0.8738 9 A. Heat Exchanger B. Thermal Cycler C. Heat Block D. Mini-Microwave 15. The polymerase chain reaction uses which molecule? A. Ribosome B. RNA polymerase II C. DNA polymerase D. RNA polymerase I 16. Which population level, allele-changing process has remained comparatively unchanged in Humans over the past 400 years? A) Mutation B) Migration C) Population size D) Natural Selection E) All have remained unchanged 17. What could cause translation to stop in a cell? A) A specific transcription factor is missing B) A promoter sequence in front of the sole Gln-tRNA encoding gene has mutated C) The DNA polymerase gene has mutated D) siRNA production has stopped E) All of the above 18. You have detected a 10-fold increase in microRNA production in human cancer cells vs a may have caused this increase? A) Overall RNA production has increased in the cancer subject B) A specific cellular control gene is being silenced C) A group of cellular control genes are being silenced D) The cellular mechanisms controlling RNA may have been damaged E) DNA polymerase is being controlled by the microRNA 26. You wish to study a previously undiscovered organism. Which data would give you a quick understanding of the organism to compare with other, known organisms? A) cDNA sequencing B) ITS sequencing C) EST sequencing D) mRNA sequencing E) All of the above 27. You have performed an extraction of a cells RNA-you discover that there are no tRNA molecules what is the most likely cause of this? A) All of the tRNA genes have become mutated B) All of the mRNA genes have become mutated C) The RNA polymerase I genes have been inactivated D) The RNA polymerase II genes have been inactivated E) The RNA polymerase IIl genes have been inactivated 28. The temperature required to separate two complimentary strands of the same DNA molecule is affected by which of the following factors? A) The G/T content of the strand B) The direction of the strand C) The G/C content of the strand D) The availability of DNA helicase E) The availability of DNA PolymeraseExplanation / Answer
Question: 11
You notice an extra chromosome in a patients karyotype – which of these conditions might be caused by the trisomic addition?
Answer: A. Pateu syndrome
Pateu syndrome: is caused by the presence of extra copy of the chromosome 13.
Parkinson’s disease:
Parkinson’s disease is the multi organ neurodegenerative disease. It affects the nervous system, olfactory, gastrointestinal tract.
Neurotransmitter dopamine is absent due to death of dopaminergic cells. Motor skills are affected; symptoms include depression, cognitive decline, sleep.
Huntington’s disease:
It is caused by the mutation in the Huntingtin gene, which causes the death of brain cells.
Turner syndrome:
Turner syndrome is caused by the missing X chromosome. The person has only 45, X chromosome.
Question: 12
Which of the following represents the best possible (not likely to be random) “e” value from a BLAST result?
Answer: C) 0.0
E-value is the expected value,it is the value that describes the number of hits that can be expected when searching the database. It decreases as the score increases. Lower the E-value or if it is close to 0, it is the significant match.
Question: 13
You have pipettedan unknown volume of water on to the scale, which reads 0.8738g,what volume have you transferred?
Answer: D. 873µl
There are 0.001g in one microlitter, so 0.8738/0.001 = 873.8 µl
Question: 14
Commonly used name for a PCR machine
Answer: B. Thermal Cycler.
PCR is also known as thermal cycler because it uses 3 different temperatures to amplify the DNA.
PCR involves 3 main steps:
Question: 15
The polymerase chain reaction uses which molecule?
Answer: C. DNA polymerase.
Explanation:
PCR technique uses Taq DNA polymerase, which is isolated form T.aquaticus. Human and other organisms DNA polymerase at high temperature loses its function, But Taq DNA polymerase is capable to with stand temperature 70?C.
Question: 28
The temperature required to separate two complementary strands of same DNA molecules is affected by which of the following factors?
Answer: C. the G/C content of the strand
Explanation:
The temperature required to separate the DNA strand depends on the G/C content of the strand because, G/C base pairing has 3 hydrogen bonds. A/T base pairing has 2 hydrogen bonds.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.