2.) Patient number 2 Patient History: o o 55 year-old female Excellent health to

Question

2.) Patient number 2 Patient History: o o 55 year-old female Excellent health to date o Recent onset of . Fatigue . Headaches . Excessive salivation . Diarrhea . Vertigo - Abdominal pain Nausea . Vomiting Weight loss o Psychological stress Recently won lottery Marital stress o Swelling of eyelids o Partial limb paralysis o Hyperkeratosis (increased pigmentation) of skin on palms & soles o White banding on fingernails o Muscle weakness Laboratory Results o Low levels of ATP production o Unusually high levels of arsenic o Abnormal levels of cell death-not due to apoptosis (programmed cell death)-rather cell death appears to be due to lack of energy to maintain homeostasis due to low ATP levels. Diagnosis o Malfunctioning Organelle: Rationale for Diagnosis (explanation of how history, physical examination and laboratory results suggest diagnosis): o

Explanation / Answer

The patient is suffering from Arsenic Poisoning. Diagnosis- The malfunctioning organ can be identified as Mitochondria.by the observation of ATP production in low levels and cell death Skin pigmentation and sweeling of eye lids and weight loss is due to gastrointestinal disorders followed by nausea ,diarrhoea,sweating and vomiting which causes dehydration and lossof salts from the body. Dizzines is accompained by weakness and low blood preesure.

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