As indicated in the BRENDA database, the classification number 2.7.1.1 refers to

Question

As indicated in the BRENDA database, the classification number 2.7.1.1 refers to ________, and ATP is a _________ in the reaction catalyzed by this enzyme.

A.hexokinase; co-product

B.phosphoglucokinase; co-substrate

C.hexokinase; co-substrate

D.phosphoglucokinase; co-product

As indicated by the BRENDA database, the enzyme hexokinase is NOT used in which pathway?

A.streptomycin synthesis

B.glycolysis

C.sucrose degradation

D.sucrose synthesis

The enzymes classified as 1.1.1.1 and 1.1.1.2 are both oxidoreductases that catalyze reversible reactions. Which cofactors are used as co-substrates by these enzymes when catalyzing reduction reactions?

A. 1.1.1.1 NADPH; For 1.1.1.2 NADH

B. For 1.1.1.1 NADP+; For 1.1.1.2 NAD+

C. For 1.1.1.1 NAD+; For 1.1.1.2 NADP+

D. For 1.1.1.1 NADH; For 1.1.1.2 NADPH

Which enzyme class does NOT use biotin as a cofactor?

A.oxidoreductases

B. transferases

C. lyases

D. Ligases

According to Table 14-1 and the BRENDA database, the oxoglutarate dehydrogenase enzyme that is specifically characterized as ___________ uses lipoic acid as a cofactor to catalyze _______________ reactions.

A. succinyl-transferring; alkyl transfer

B. NADP+-dependent; acyl transfer

C. NADP+-dependent; alkyl transfer

D. succinyl-transferring; acyl transfer

In the KEGG database, the pathway map for glycolysis/gluconeogenesis indicates that ___ unique enzyme/s can catalyze the conversion of ?-D-glucose to ?-D-glucose-6-phosphate (?-D-glucose-6P).

A. 3

B. 1

C. 2

D. 4

How many steps are required to convert ?-D-glucose-6-phosphate (?-D-glucose-6P) to glycerate-1,3-bisphosphate (glycerate-1,3P2)?

A. 2

B. 6

C. 4

D. 5

Among the steps highlighted in question 7, which enzyme catalyzes an irreversible reaction?

A. fructose-bisphosphate aldolase

B. glucose-6-phosphate isomerase

C. 6-phosphofructokinase 1

D. glyceraldehyde-3-phosphate dehydrogenase

As indicated in the KEGG pathway map, the reaction catalyzed by hexokinase (2.7.1.1) is irreversible; according to the BRENDA database, which metabolite inhibits this enzyme?

A. ATP

B. AMP

C. Citrate

D. All of these metabolites inhibit hexokinase.

Explanation / Answer

1. C.hexokinase; co-substrate

2. D.sucrose synthesis

3. D. For 1.1.1.1 NADH; For 1.1.1.2 NADPH

4. A.oxidoreductases

5. D. succinyl-transferring; acyl transfer

6. C. 4

7. C. 6-phosphofructokinase 1

8. D. All of these metabolites inhibit hexokinase.

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