Activity F. The ABO blood groups ABO blood groups are the most commonly known bl

Question

Activity F. The ABO blood groups ABO blood groups are the most commonly known blood groups. Rh factor is another commonly known blood group. But in all fairness humans are much more complicated than that. There are currently over 300 different types of blood factors known to hematologists. ABO is arn acronym for the three types of alleles an individual may potentially have. Of course a diploid individual can only have 2 alleles. The genotypes and phenotypes of different combinations of the three alleles are given in Table1. Phenoty Genotypes BB. BO or IBBi OO or i AB Table 1 Blood Types These are the most common blood type phenotypes and genotypes seen in humans. Notice that phenotypes A and B can have two possible genotypes. Notice also that blood types AB and O only have 1 possible type of genotypes. This situation is a pattern of inheritance referred to as co-dominance. The allele A is dominant to the allele O. The allele B is dominant to the allele O, but the allele A is co-dominant to the allele B, hence the phenotypic blood type AB The Rh blood factor's pattern of inheritance is the case of simple dominance that we have been assuming in this lab till now. The Rh blood factor is inherited as a single pair of alleles. Rh positive (Rh') is dominant to Rh negative (Rh). Use the information in Table 1 and the above paragraph to answer questions 1 through 3. 1. A boy wonders if he is adopted. He compares his blood type to those of his parents a. If the father is blood type AB and the mother is blood type O, what blood types would indicate that the child might have been adopted? b. If the father is blood type A and the mother is blood type B would blood typing help the boy determine if he was adopted? 2. If you are Rh' can you know your genotype for sure? Why? 3. If you are Rh' and everybody in your family is Rh (parents, siblings, offspring) what is/are your probable genotype(s)? Why? Do you know your genotype with absolute certainty? Explain.

Explanation / Answer

1. a. If the father is having AB blood group., then he can give his child either A or B, but not both. Since, mother is having O blood group, she can give O blood group. Hence, the child can not have AB blood group. Hence, if child is having AB blood group , then only he or she is adopted.

b. If the father is having A blood group and mother is B blood group, so a child can have A, B AB or O blood group. Hence. It is difficult to find whether the children is adopted or not.

2. If my blood group is Rh negative, then my genotype will be - and -. Yes, this genotype will be sure as it a recessive trait.

3. If my blood group is Rh positive, then my genotype is either +,- or +,+ as Rh+ve is a dominant trait. No, I would not be sure of the genotype as it could be because of +,- or +,+

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