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6. After acing midterm 2 in Biochem 442 your PI, Dr. Peach, now believes you are

ID: 272307 • Letter: 6

Question

6. After acing midterm 2 in Biochem 442 your PI, Dr. Peach, now believes you are ready to take on a collaborative project with Dr. Rosalina. Dr. Rosalina is interested in a new Yoshi species She tells you that this species has patches of white, orange, and black scale phenotype. Dr Rosalina also noticed that this only occurs in female Yoshi's A) After learning so much in Biochem 442, you had an eureka moment and You remember learning about spotted coats in Biochem 442, therefore you tell Dr. Rosalina your molecular explanation of how only female Yoshi's can have this color pattern phenotype In your explanation, please also provide an example given in class that demonstrated this (4pts) B) Dr. Rosaline was impressed with your explanation from part (a) and therefore decides to give you another project. This project focuses on gene loci that may be involved in imprinting. She wants you to find a loci that is involved in imprinting. So you sequenced a chromosome in a Yoshi cell that contains the kcnq1 loci. You found that in the (maternal/paternal) chromosome, there is a methylation mark within the (maternal/paternal), end of the kcnq1 gene. You also found that in the there is no methylation mark.

Explanation / Answer

Ans-A this colour pattern seen only in females because the gene responsible for colour pattern is linked with X chromosome. The other possible reason may be that the responsible gene may not be Express in males because of some mutation.

Ans-B 1) Maternal . 2) paternal

Ans-C it is so because there is no Kcnq1 gene present at the loci in paternal chromosomes. The diagram attached in question is correctly stating this.

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