9. Hemoglobin allows red blood cells to transport oxygen. This protein is made o
ID: 271907 • Letter: 9
Question
9. Hemoglobin allows red blood cells to transport oxygen. This protein is made of 4 polypeptides; each polypeptide is made of a specific sequence of about 150 amino acids. When the arrangement of amino acids differs from the normal one, the hemo- obin formed cannot transport oxygen efficiently and sickle-cell anemia results. The lowing amino acid sequence represents a piece of the normal hemoglobin molecule. Translate the sequence of amino acids in normal hemoglobin into: proline glutamate glutamate lysine a. tRNA anticodons b. mRNA codons cCC GAAGAAAAA c. DNA template. In sickle-cell anemia, a mutation results in a different sequence of amino acids. Trans late this sequence of amino acids in sickle-cell hemoglobin into: proline valine glutamate lysine a. tRNA anticodons b. mRNA codons CCC c. DNA template GUA GAA AAA 10. In terns of nucleotides explain the only difference between the DNA message for nor- mal hemoglobin and the DNA message for sickle-cell hemoglobin. 11. If you change the order of the nucleotides in a gene, how might the resulting polypep- tide be affected? 12. What is the process that passes mutations on to offspring? 13. What molecule is created at transcription? 14. What is the function of ribosomal-RNA? 15. What is the function of transfer-RNA? 16. What molecule is created at translation? 17. What is being translated? 126Explanation / Answer
9-A- Ggg cuu cuu uuu
C-ggg ctt ctt ttt
A-ggg cau cuu uuu
C- ggg cat ctt ttt
Note -the na template strand and anticodon both are complimentary to mrna sequence of codon .
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