The Kidd blood group in primates is inherited as a single gene with 2 Codominant
ID: 271831 • Letter: T
Question
The Kidd blood group in primates is inherited as a single gene with 2 Codominant alleles (Jka and Jkb). We would like to verify that this locus actually follows simple Mendelian inheritance with codominant alleles in gibbons. We have a pure breeding population of Type Jka & a pure breeding population of Type Jkb.
We create an F2 population and test for the antigens.
Jka: 41
Jka Jkb: 56
Jkb: 35
Perform a chi square analysis on this data using the following hypothesis: The mode of inheritance for the Kidd blood group in gibbons is simple Mendelian with codominant alleles. Calculate the chi square value and place it in the space below. Round to three decimal places.
Explanation / Answer
Null hypothesis: The observed values are not deviating from the 1:2:1 ratio.
Test static – Chi-square test:
Category
Jka
Jka Jkb
Jkb
Total
Observed values
41.00
56.00
35.00
132
Exptected Ratio
1
2
1
4
Exprected Values
33
66
33
Deviation
8
-10
2
D^2
64
100
4
D^2/E
1.939394
1.515152
0.121212
3.575758
X^2
3.575758
Degrees of freedom
3-1=2
Inference: The calculated chisquare value i.e. 3.57 is lessthan the table value i.e. 5.99 at 2 DF and 0.05 probability, hence the null hypothesis is accepted.
Category
Jka
Jka Jkb
Jkb
Total
Observed values
41.00
56.00
35.00
132
Exptected Ratio
1
2
1
4
Exprected Values
33
66
33
Deviation
8
-10
2
D^2
64
100
4
D^2/E
1.939394
1.515152
0.121212
3.575758
X^2
3.575758
Degrees of freedom
3-1=2
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