PLEASE SHOW WORK... THANK YOU!! Genotypes: A1/A1: 80 A1/A2: 20 A2/A2: 90 Total:

Question

PLEASE SHOW WORK... THANK YOU!!

Genotypes:

A1/A1: 80

A1/A2: 20

A2/A2: 90

Total: 190

1. Use the data above to estimate the frequency of the two alleles. Be sure it is clear which frequency corresponds to which allele.

2. Use your answers from question 1 to calculate the EXPECTED FREQUENCY for each of the three genotypes

3. Use your answers from question 2 to calculate the EXPECTED NUMBER for each of the three genotypes

4. Use a X2 test to determine if your population sample conforms to the expected Hardy-Weinberg proportions. Provide a clear statement of how you would interpret the results of this test

5. If the population is in Hardy-Weinberg proportions, explain what that means. If the population does not appear to be in Hardy-Weinberg proportions, propose a mechanism that might account for the observed pattern and briefly explain your answer.

Explanation / Answer

It is given that, the frequency of A1A1 or p2 is = 80/190 or 0.421

The frequency of A1A2 or 2pq is = 20/190 = 0.105

The frequency of A2A2 or 2pq is = 90/190 = 0.473

The frequency of A1 allele or p is = Frequency of p2 + ½ (2pq) = 0.421 + ½ (0.105) = 0.4735

The frequency of A2 allele or q is = Frequency of q2 + ½ (2pq) = 0.473 + ½ (0.105) = 0.525

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