Human Immunodeficiency Virus (CHIV) is the causative agent of Acquired and Immun

Question

Human Immunodeficiency Virus (CHIV) is the causative agent of Acquired and Immunodeficiency Syndrome (AIDS). Post infection and during initial symptoms acute infection, the patient experience flu-like symptoms. During the acute pse infection, the individual is unaware of infection. However, as time pass, chroni infection occurs with a gradual decline in immunity with occurrence of opportunistic infection. During your tenure as a clinician, you encountered a twenty-f in the emergency room with fever and oral thrush with no diagnosis. Oral thrush has several mechanism of cause: Those included immunosuppression, chemotherapy du cancers and the you are not certain. As a clinician, what questions would you ask the patient to determine the best route of diagnostic determination? And accordingly, what diagnostic, molecular tools would you utilize to determine proper cause for his fever and oral thrush? e to use of broad spectrum antibiotics. You suspect immunosuppression, but

Explanation / Answer

Generally the HIV patients undergo immunosuppression, due to this there will be a occurrence of secondary infection. Where opportunistic pathogens causes infections. The patients with HIV mostly show symptoms like oral thrush and fever. Generally the fever occurs due to secondary bacterial infections. The oral thrush which is known as oropharyngeal candidiasis where yeast shaped fugus called candida grow in mouth and cause infection. Generally this fungus is opportunistic pathogen. Generally the clinician check the patient mouth whether the presence of white patches on the tongue, inner cheeks and back of the throat which are common symptoms caused by candida. The molecular tools used for identification of this organism RFLP using DNA-DNA hybridisation or gel electrophoresis. Species specific PCR approches and flourocent in aiti hybridisation also used for identification of candida albicans.

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