47. On average 30 new SNPs are created in each genome passed on in a gamete. For

Question

47. On average 30 new SNPs are created in each genome passed on in a gamete. For example, about 30 new SNPs were created in the genome that you inherited from your mother and another 30 new SNPs were created in the genome that you inherited from your father. These SNPs are referred to a "private alleles" because they are unlikely to exist in other people A. Given that 30 new SNPs are created in each 3 bilion base pairs that get passed on in a gamete, how likely is it for a specific letter in the genome to be acquire a SNP mutation when passed to the next generation in a gamete? Show how you derived your answer. B. Re-write your final answer (a number) as a word rather than a numeral. Page 1

Explanation / Answer

Ans.

a) As, 30 new SNPs are created in each 3 billion base pairs i.e., 3 * 109 bp ,

probability for a specific letter to acquire SNP mutation will be = 30 / 3 * 109 = 10^ -8

b) A specific letter will acquire mutation once in 1 hundred million events of gamete formation.

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