??{? 95% 1 4:04 PM Docs Viewer MYC is a transcription factor that increases the

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??{? 95% 1 4:04 PM Docs Viewer MYC is a transcription factor that increases the expression of genes that are important for cell proliferation and survival. Overexpression of MYC protein is a common feature of many types of cancer cells. When MYC is overexpressed in NORMAL cells the result is not excessive cell proliferation, but cell-cycle arrest and apoptosis (1) Why would MYC be considered an oncogene rather than a tumor suppressor? a. b. c. d. Myc is an oncogene, because it regulates cell proliferation Myc is an oncogene, because overactivation of Myc leads to cancer Myc is a tumor suppressor, because it regulates apoptosis. Myc is tumor suppressor, because mutation in Myc would alter the rate of apoptosis (2) What might need to occur in normal cells in addition to overexpression of MYC to produce the excessive cell proliferation phenotype? Mutation in a growth factor receptor Mutation in Ras Mutation in pS3 a. b. c. Learn Marketing Skills Quick Marketing Lessons INSTALL

Explanation / Answer

1.b. Myc is an oncogene, because overactivation of Myc leads to cancer.

2. b. Mutation in Ras

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