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You decide to test the three hypotheses from Part A by making expression constru

ID: 264557 • Letter: Y

Question

You decide to test the three hypotheses from Part A by making expression constructs that combine different DNA regions from the affected child and her older brother, who has normal mRNA expression. As controls, you make full- ength constructs from both of these children. The construct made entirely from the older brother's DNA (construct 2 below) has normal expression in tissue culture cells, while the construct from the affected child (construct 1) has no For each of the three hypotheses, predict if each construct will express mRNA Complete the table by dragging the "yes" and "no" labels to the correct locations. Use the "Yes" label if you predict a construct will express mRNA if the indicated explanation for the mutation is correct (each column is one of the 3 possible explanations) . Use the "No" label if you predict no expression for the given construct if the explanation in that column were true. Reset Help Regulatory DNA Promoter Transcribed region Yes No No No 1 Affected child Affected child 2. Older brother Older brother 3. Older brotherOlder brother Affected child Older brother Affected child Affected child Older brother Affected child Older brother Older brother No Yes YeYes . Older brother

Explanation / Answer

You decide to test the three hypotheses from Part A by making expression constru

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