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Upon being secreted from the pancreas, glucagon binds to the receptors on liver

ID: 263798 • Letter: U

Question

Upon being secreted from the pancreas, glucagon binds to the receptors on liver cells, which initiates a signaling cascade that regulates glycogen metabolism, glycolysis/gluconeogenesis, and fatty acid metabolism. Explain the following:

1. The metabolic conditions in which glucagon is released from the pancreas

2. How it affects metabolism of glycogen, glucose (glycolysis/gluconeogenesis), and fatty acids

3. Why it makes metabolic sense for glucagon to regulate these pathways in this manner in the liver cells.

Explanation / Answer

Upon being secreted from the pancreas, glucagon binds to the receptors on liver

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