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Human blood type is determined by three alleles IA , IB , and IO . The alleles I

ID: 263517 • Letter: H

Question

Human blood type is determined by three alleles IA , IB , and IO . The alleles IA and IB are co-dominant to each other, and both are dominant to IO . Within a large, randomly mating population (540,000 individuals), the frequencies for the blood type alleles are 0.3 for the IA allele, 0.6 for IO , and 0.1 for the IB allele. However, every generation, approximately 10,800 people from a neighboring population travel over a mountain range and settle into this original population. The frequencies for the blood type alleles in the migrating population are 0.6 for the IA allele, 0.2 for the IO allele and 0.2 for the IB allele. If the population is maintained at 540,000 individuals, what will be the frequencies of IA , IO and IB in the next generation?

Explanation / Answer

Human blood type is determined by three alleles IA , IB , and IO . The alleles I

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