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Q1. In the pedigrees below, D and d are alleles of a disease gene and 1 and 2 al

ID: 263322 • Letter: Q

Question

Q1. In the pedigrees below, D and d are alleles of a disease gene and 1 and 2 alleles of a second locus. dd22 Ddl2 Dd12 ddl1 Dd12 III Dd11 dd12 Ddl1 Pedigree 1 Pedigree 2 a) For Pedigree 1: Give the linkage phase of individual Il.2 b) For Pedigree 1: Which individuals of generation Ill are recombinant and which are non-recombinant? c) For Pedigree 2: Explain why the linkage phase of individual I.2 cannot be determined, and then explain why this means the individuals of generation Il cannot be classified as recombinant (R) or non recombinant (NR)

Explanation / Answer

Q1. In the pedigrees below, D and d are alleles of a disease gene and 1 and 2 al